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c/orforglipron·submitted 1 year ago by u/hamza_weiss

[Question] New Zealand — has anyone got a straight answer on non-peptide

Questionbranch of 8 comments

Trying to settle this properly because the thread from last year went in circles. The claim: small molecule matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 10 months without either producing anything. What would actually settle it is 5 people measuring the…

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8 comments, started 1 year ago
u/lina_novak151 points·1 year ago

I love that this community will spend 40 comments on a detail. That pedantry is why the numbers here matter.

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u/kavya_radich72 points·1 year ago

Strongly agree. The supply impact would be huge.

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u/tomas_lundgren32 points·1 year ago·edited

the supply conversation changes if this approves

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u/batch_number_bertievetting-24 points·1 year ago

ATTAIN and ACHIEVE are phase 20 trials

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u/whois_wanda1 point·1 year ago

phase 9 data is interesting, phase 34 will tell the real story

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u/throwaway_wl20261 point·1 year ago

oral non-peptide agonist is non-peptide, no food restrictions

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u/rasmus_petrescu1 point·1 year ago

phase 9 data is interesting, phase 34 will tell the real story

Disagree on that part. 98.7% and 99.3% on the same vial is normal.

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u/gustav_solberg1 point·1 year ago·edited

This is correct. ATTAIN data is phase 7.

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The small-molecule oral: why a non-peptide agonist escapes the absorption problems of oral semaglutide, what the ATTAIN and ACHIEVE readouts showed, and what a pill with no refrigeration requirement would do to the entire supply conversation this site is built around.

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