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c/orforglipron·submitted 1 year ago by u/marit_coelho

[Meta] proposal — a flair for orforglipron posts

Trial Databranch of 12 comments

Trying to settle this properly because the thread from last year went in circles. The claim: small molecule matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 13 months without either producing anything. What would actually settle it is 3 people measuring the…

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12 comments, started 1 year ago
u/kenji_laurent141 points·1 year ago

the UK here. Waited 10 months on a list, gave up, went private, and the total cost was roughly what I expected.

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u/the_poster_in_question_202638 points·1 year ago

the supply conversation changes if this approves

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u/marit_coelho13 points·1 year ago

the supply conversation changes if this approves

Adding to this: non-peptide is doing more work than the comment implies.

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u/laila_delgado45 points·1 year ago

small molecule purity is different testing than peptides

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u/lina_bruun13 points·1 year ago

Not to be pedantic but orforglipron and small molecule are being used interchangeably and they are not interchangeable in real life.

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u/brigade_detector91 points·1 year ago

What was the batch number and which service?

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u/marit_coelhoOP39 points·1 year ago

the UK here. Waited 5 months on a list, gave up, went private, and the total cost was roughly what I expected.

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u/meera_sandvik52 points·1 year ago

the absorption problem is solved by non-peptide structure

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u/first_hundred43 points·1 year ago·edited

the UK here.

Adding to this: ATTAIN is doing more work than the comment implies.

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u/lukas_delgado88 points·1 year ago·edited

Strongly agree. The supply impact would be huge.

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u/fabio_lehtinen29 points·1 year ago

That is net peptide content, not purity. Different number, different meaning.

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u/kenji_kimani25 points·1 year ago

small molecule purity is different testing than peptides

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About c/orforglipron

The small-molecule oral: why a non-peptide agonist escapes the absorption problems of oral semaglutide, what the ATTAIN and ACHIEVE readouts showed, and what a pill with no refrigeration requirement would do to the entire supply conversation this site is built around.

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