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why does nobody talk about goal weight

Question Well Actually ×5 Slow Clap ×1

Confession thread, sort of.

I went from 2.5mg to 1.0mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 2 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway.

So now I have early fullness I did not need and a data point I cannot interpret. Two lessons in one.

Posting it in the hope that somebody at week 35 reads it before doing the same thing.

2,318 up / 233 down91% upvoted57 commentsid pbyas926 Jun 2025

57 comments

23 in this archive, depth 6

best — the order this archive was captured in

u/brigade_detector223 points·1 year ago

the lowest dose you can stay on is not the lowest dose that works

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u/camila_sandvik135 points·1 year ago

the lowest dose you can stay on is not the lowest dose that works

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/ewan_marchand-31 points·1 year ago

Water content matters more than people think. If a vial is carrying residual moisture, your "10mg" is not 10mg of peptide.

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u/honest_syringe1 point·1 year ago

Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.

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u/noor_cardoso122 points·1 year ago

Strongly agree. Lowest effective dose is a real discovery process.

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u/nadia_nascimento37 points·1 year ago·edited

Yeah, maintenance is the boring part and the important part.

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u/constipation_clubOPside effects88 points·1 year ago

Regain on a taper is expected. 4% back over 16 weeks, which matches the discontinuation data. Planned for it.

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u/food_noise_gonemaintenance57 points·1 year ago

food noise returns but not always immediately

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u/constipation_clubOPside effects34 points·1 year ago

Tried the lowest-effective approach. 0.25mg worked for 18 weeks, then cravings returned. 12.5mg was the actual floor.

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u/sena_balogun30 points·1 year ago

state how long you have been at maintenance, week 23 is not maintenance

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u/usp_appendixcompendial13 points·1 year ago

Yeah, maintenance is the boring part and the important part.

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u/andres_dahlberg6 points·1 year ago

lowest effective dose is dose stretching, find it or stay higher

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u/cesar_oyelaran95 points·1 year ago·edited

What dose are you on?

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[removed]70 points·1 year ago

[removed by moderator]

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u/blunt_coldbox_notes75 points·1 year ago

food noise returns but not always immediately

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u/blunt_coldbox_notes85 points·1 year ago
tl;dr for anyone scrolling: regain
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u/still_here_2026104 points·1 year ago

Weight variance within what range?

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u/constipation_clubOPside effects42 points·1 year ago

the long term question changes at maintenance

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u/hugo_norgaard18 points·1 year ago

the 12.5mg dose works fine for 37 weeks of the month

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u/nabila_espinoza44 points·1 year ago

the plateau is where the learning happens

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u/zeynep_mbeki28 points·1 year ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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u/andres_dahlberg39 points·1 year ago

You have restated the marketing copy. What is the actual substance here.

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About c/maintenancephase

The part nobody posts about: what happens at goal weight. Finding a lowest effective dose, dose-interval stretching, regain risk data, muscle retention, the psychology of not having a number to chase, and staying on indefinitely versus tapering.

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c/maintenancephase rules
  1. State how long you have been at maintenance. "Maintenance" at week 30 is not maintenance.
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