lowest effective dose — 4 things I got wrong before I got it right
Genuinely asking, not being difficult. Everyone in c/trialwatch repeats that goal weight is important. I believe it, but I have never seen anyone show why, and when I search I get 9 threads of people agreeing with each other. Is there a paper? Is there a measurement? Or is this one of those things that is true…
The plateau is real and boring. 28 weeks at the same weight, then movement again. Patience was the intervention.
the plateau is where the learning happens
Small correction: the trial was 21 weeks, not 20. Does not change your point but people will quote it.
Strongly agree. Lowest effective dose is a real discovery process.
No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.
state how long you have been at maintenance, week 13 is not maintenance
the lowest dose you can stay on is not the lowest dose that works
Yeah, maintenance is the boring part and the important part.
weight moves within 3kg and that is normal
Regain on a taper is expected. 6% back over 12 weeks, which matches the discontinuation data. Planned for it.