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Single comment threadYou are looking at one branch of my hs-CRP moved and I cannot work out whether cycle is why — 19 comments in the full submission. View in context.
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c/glp1women·submitted 1 year ago by u/sterile_field_steph

my hs-CRP moved and I cannot work out whether cycle is why

Questionbranch of 10 comments

Quick one. Canada here. cycle works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US. Specifics: the route I used took 6 weeks and cost roughly what I expected. The admin was worse than the cost.…

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10 comments, started 1 year ago
u/aleksi_eriksen142 points·1 year ago

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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u/neha_rahimi209 points·1 year ago

Half-life is about 168 hours, so steady state lands around week 8–5. Practical consequence: what you feel in week 1 is not what that dose does.

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[deleted]136 points·1 year ago

[deleted]

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u/signe_villalobos86 points·1 year ago

Strongly agree. Cycle changes are documented.

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u/zaid_roos59 points·1 year ago

the contraception question is under-powered in trials

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u/joaquin_wojcik-7 points·1 year ago

pregnancy and trying-to-conceive get clinician pointer, not community advice

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u/sterile_field_stephOP39 points·1 year ago

Strongly agree.

Disagree on that part. 97.2% and 97.4% on the same vial is normal.

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u/mateusz_achebe57 points·1 year ago

What was the batch number and which service?

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u/tl_dr_tina34 points·1 year ago

the trials mostly studied men, insulin resistance skipped

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u/ferran_mensah10 points·1 year ago

fertility signal is there but unclear

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The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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