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108
c/glp1women·posted 2 months ago by u/hair_shed_hannah

does cycle actually matter or is it forum lore at this point

Caution

Trying to settle this properly because the thread from last year went in circles.

The claim: cycle matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 3 months without either producing anything.

What would actually settle it is 35 people measuring the same thing the same way. I have started; my numbers are below. They lean one way but not strongly enough for me to declare victory.

If you have data, post the data. If you have an opinion, flair it as an opinion.

175 up / 67 down72% upvoted12 commentsid 132ooh14 May 2026

12 comments

12 in this archive, depth 5

best — the order this archive was captured in

u/coa_forgery_watch16 points·2 months ago

Crossposting this to c/darkspot because the people who need it are not reading this community.

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u/low_appetite_lisa4 points·2 months ago·edited

This is correct. PCOS is real.

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u/ferran_mensah5 points·2 months ago

Came off after 76 weeks for financial reasons. Regained about a third over the following year. Back on now at a much lower dose.

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u/elodie_kuipers11 points·2 months ago

Crossposting this to c/darkspot because the people who need it are not reading this community.

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u/hair_shed_hannahOP8 points·2 months ago

the perimenopause question is under-powered in trials

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[removed]4 points·2 months ago

[removed by moderator]

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u/tired_ledger_ftw-28 points·2 months ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/hair_shed_hannahOP1 point·2 months ago

pregnancy and trying-to-conceive get clinician pointer, not community advice

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u/hair_shed_hannah8 points·2 months ago

Every time this gets posted it hits the front page and every time someone has to re-explain it.

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u/aleksi_grimaldi12 points·2 months ago

This is correct. PCOS is real.

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u/micro_bump_mick5 points·2 months ago

The reflux was genuinely awful for three weeks and then simply stopped. I know that is not useful information, but it is what happened.

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About c/glp1women

The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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c/glp1women rules
  1. Pregnancy and trying-to-conceive questions get a clinician pointer, not community advice.
  2. Contraception interaction claims need a citation.
  3. No cycle-tracking data with identifying details.
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  5. Not medical advice. Describe what you did; never prescribe to a stranger.
  6. Claims need evidence. Batch numbers, dated screenshots, independent test reports, or a citation.
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