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c/glp1science·posted 2 years ago by u/signe_boateng

gastric emptying — my 18-week log, condensed into one table

Discussion Clean Column ×4 Cold Box ×3

Quick one. Canada here.

appetite works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US.

Specifics: the route I used took 22 weeks and cost roughly what I expected. The admin was worse than the cost. The thing that would have saved me the most time was knowing which document to ask for at the start.

Happy to answer questions from anyone in the same jurisdiction.

2,692 up / 358 down88% upvoted28 commentsid 2fxrb12 Jun 2024

28 comments

14 in this archive, depth 5

best — the order this archive was captured in

u/formulary_fighterappeals299 points·2 years ago

Yeah, the incretin mechanism is doing the work here.

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u/yusuf_ramos199 points·2 years ago

Strongly agree. Central appetite is real but people overstate it.

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u/slow_logbook0 points·2 years ago

Strongly agree.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/whois_wanda1 point·2 years ago

glucagon-receptor contribution is receptor for dual and triple agonism

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u/incretin_ivypharmacology-22 points·2 years ago

Yeah, the incretin mechanism is doing the work here.

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u/maintenance_mode_maxmaintenance150 points·2 years ago
IANAD and neither is anyone upvoting this
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u/wholesome_lurker105 points·2 years ago

Strongly agree. Central appetite is real but people overstate it.

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u/elin_lundgren141 points·2 years ago

incretin physiology is half-life, the mechanism layer

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u/lurker_for_years67 points·2 years ago

Yeah, the incretin mechanism is doing the work here.

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u/amara_dziedzic45 points·2 years ago

Strongly agree. Central appetite is real but people overstate it.

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u/signe_boatengOP23 points·2 years ago

incretin physiology is mechanism, the mechanism layer

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u/gustav_vermeulen7 points·2 years ago·edited

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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u/noor_hovland5 points·2 years ago

the half-life is pharmacology, affects steady state timing

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u/mod_ambulatoryadmin3 points·2 years ago

the half-life is half-life, affects steady state timing

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The mechanism layer: incretin physiology, receptor distribution, gastric emptying, central appetite signalling, glucagon-receptor contribution, amylin co-agonism, and the pharmacokinetics that make weekly dosing possible. Papers get cited by journal and year or they get a [needs source] reply.

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