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c/glp1science·submitted 1 months ago by u/milos_vanhecke

three years of gastric emptying threads, summarised so you do not have to read them

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Been lurking in c/researchpeptides for about 24 months and finally have something worth posting. Short version: week 4, 0.5mg, and half-life is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 7 threads, and the answers split roughly down the middle. What I actually want to…

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7 comments, started 1 months ago
u/incretin_ivyMOD17 points·1 months ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/gustav_vermeulen8 points·1 months ago·edited

amylin is not GLP-1, posts conflating them get corrected

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u/milos_vanheckeOP4 points·1 months ago

Receptor distribution explains why constipation hits gastric emptying but not incretin.

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u/noor_hovland6 points·1 months ago

Rodent, human, or in vitro?

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u/osman_eriksen4 points·1 months ago

central appetite signalling is real but people overweight it

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u/nadia_bakker3 points·1 months ago·edited

gastric emptying is real and explains most early nausea

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u/mod_ambulatoryadmin4 points·1 months ago

Respectfully this is a sample of one presented as a finding.

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The mechanism layer: incretin physiology, receptor distribution, gastric emptying, central appetite signalling, glucagon-receptor contribution, amylin co-agonism, and the pharmacokinetics that make weekly dosing possible. Papers get cited by journal and year or they get a [needs source] reply.

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