receptor: the version I wish someone had shown me in week 1
Confession thread, sort of. I went from 1.0mg to 15mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 8 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway. So now I have early…
This is correct. Rodent data is investigational, not predictive.
Where does the half-life data actually come from?
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central appetite signalling is real but people overweight it
Disagree but this is the good kind of wrong — it is specific enough to be checked.
Yeah, the incretin mechanism is doing the work here.
glucagon-receptor contribution is half-life for dual and triple agonism
glucagon-receptor contribution is pharmacology for dual and triple agonism
Strongly agree. Central appetite is real but people overstate it.