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glucagon receptor agonism raising energy expenditure — how solid is that
Been lurking in c/trialwatch for about 12 months and finally have something worth posting. Short version: week 22, 0.25mg, and receptor is the bit I still cannot get a…
u/anya_salgado
Contributes reviews on supplier material. Based in Mysuru.
member · joined 13 Apr 2025
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comment on [Seizure] letter arrived, no prosecution, here is exactly what it said in c/customs · 10 points · 3 days ago
the customs status depends on what happens at the border
comment on [Failure] 61.2% purity on a vial i had already been using for six weeks in c/darkspot · 15 points · 5 days ago
Not convinced. The evidence does not support that reading.
comment on why does GIP agonism seem to reduce nausea rather than add to it in c/glp1science · 74 points · 8 days ago
Rodent, human, or in vitro?
comment on glucagon receptor agonism raising energy expenditure — how solid is that in c/glp1science · 5 points · 18 days ago
Strongly agree. Central appetite is real but people overstate it.
comment on [Titration] stayed at 0.5 for eleven weeks and it was the right call in c/semaglutide · 50 points · 18 days ago
Yeah, 37 weeks on 1.7mg, same pattern, same timing.
comment on [Failure] vendor vanished mid-order with 11 people waiting in c/darkspot · 3 points · 18 days ago
Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.
comment on [Question] does anyone have a straight answer on transit vs destination liability in c/customs · 29 points · 19 days ago
no advice on evading inspection or misdeclaring
comment on glucagon receptor agonism raising energy expenditure — how solid is that in c/glp1science · 20 points · 19 days ago
Disagree but this is the good kind of wrong — it is specific enough to be checked.
comment on glucagon receptor agonism raising energy expenditure — how solid is that in c/glp1science · 65 points · 20 days ago
Which paper are you quoting?
Adding to this: appetite is doing more work than the comment implies.
comment on [Regret] told my whole family, then stopped, then had to tell them that too in c/darkspot · 12 points · 21 days ago
no piling on, mistake posts are favours to the community
comment on [Needs Source] "it heals your metabolism" is not a mechanism in c/glp1science · 1 points · 21 days ago
do not extrapolate rodent data to human dosing without saying so
comment on [Data] 41 lanes, 900 data points, transit temperature by carrier in c/coldchain · 80 points · 26 days ago
This is correct. Dry powder is way more robust than liquid.
comment on [Discussion] we talk about dose like it is a score and it is not in c/semaglutide · 78 points · 26 days ago
Right, and the corollary is that stopping escalation does not reset your tolerance, it just pauses the clock.
comment on half-life — my 3-week log, condensed into one table in c/glp1science · 90 points · 1 months ago
Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.
comment on am I the only one who found data logger harder than the injections in c/coldchain · 9 points · 1 months ago
lane reports need origin, destination, carrier, and actual transit days
comment on am I the only one who found data logger harder than the injections in c/coldchain · 137 points · 2 months ago
Disagree but this is the good kind of wrong — it is specific enough to be checked.
comment on unpopular opinion: seizure is massively overrated in c/customs · -25 points · 2 months ago
always state your country, advice from another jurisdiction can harm you
comment on help me understand appetite, I have read the wiki twice in c/glp1science · -21 points · 2 months ago
Strongly agree. Central appetite is real but people overstate it.
comment on week 16 check-in — 17kg down, fatigue manageable, one thing confusing me in c/semaglutide · 41 points · 2 months ago
okay but what dose of sema are you on