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c/compounding·posted 2 years ago by u/controversial_only

compounding vs 503A — genuinely asking which matters more

Pricing

Long-ish post, sorry. tl;dr at the bottom.

I have been tracking API source against eGFR for 31 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here.

Caveats up front: one person, one lab, one assay, no control, and I changed my training in the middle of it, which was stupid.

tl;dr: probably real, definitely smaller than the threads imply, and not worth reorganising your week around.

12 up / 18 down40% upvoted10 commentsid kkefkc8 Dec 2023

10 comments

10 in this archive, depth 3

best — the order this archive was captured in

u/prior_auth_painMOD6 points·2 years ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/ilias_cabrera4 points·2 years ago

shortage list status is 503A, check the actual list

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u/swirl_dont_shakereconstitution4 points·2 years ago

Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.

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u/camila_mensa2 points·2 years ago

Small correction: the trial was 8 weeks, not 17. Does not change your point but people will quote it.

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u/kian_ferreira1 point·2 years ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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u/emeka_chowdhury5 points·2 years ago

the shortage list is temporary, it ends and compounding becomes illegal again

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u/bilal_osei2 points·2 years ago

What is the actual shortage list status right now?

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u/medutest_mel3 points·2 years ago

the shortage list is temporary, it ends and compounding becomes illegal again

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u/discount_math_dm3 points·2 years ago

the shortage list is temporary, it ends and compounding becomes illegal again

Yes, exactly this, and it is the bit that took me 62 weeks to accept.

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u/controversial_only2 points·2 years ago

Which state? Rules vary.

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About c/compounding

Compounded GLP-1s as a supply route: the 503A/503B distinction, the shortage-list mechanics that made compounding legal and then didn't, state board rules, telehealth prescriber models, and what a compounding pharmacy will and will not tell you about its API source.

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