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c/compounding·posted 1 year ago by u/lukas_vermeulen

[Discussion] we are measuring 503B at the wrong time and calling it noise

Discussion Sourced ×4

Quick one. Canada here.

shortage list works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US.

Specifics: the route I used took 12 weeks and cost roughly what I expected. The admin was worse than the cost. The thing that would have saved me the most time was knowing which document to ask for at the start.

Happy to answer questions from anyone in the same jurisdiction.

943 up / 332 down74% upvoted32 commentsid 1k32pu4 Jan 2025

32 comments

23 in this archive, depth 4

best — the order this archive was captured in

u/step_therapy_s139 points·1 year ago

Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.

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u/lukas_vermeulenOP63 points·1 year ago

The telehealth + compounding combo cost 503A plus 24% markup. Not cheap but covered by insurance depending on state.

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u/rekha_mwangi97 points·1 year ago

Yeah, 503A and 503B are different regulatory animals.

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[removed]37 points·1 year ago

[removed by moderator]

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u/rekha_mwangi-34 points·1 year ago

Respectfully this is a sample of one presented as a finding.

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u/step_therapy_s20 points·1 year ago

state board rules differ, say which state

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u/kavya_kravchenko13 points·1 year ago

Not to be pedantic but compounding and API source are being used interchangeably and they are not interchangeable in real life.

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u/elise_ramos58 points·1 year ago·edited

Strongly agree. API source transparency matters.

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u/sigrid_kaufmann38 points·1 year ago

telehealth costs 503A plus compounding markup, total varies

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u/santiago_rasmussen32 points·1 year ago

503B compounding is different from 503A, different rules, different legality

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u/lukas_vermeulenOP13 points·1 year ago

the 503A/503B distinction is load-bearing, do not blur it

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u/anya_antonsen17 points·1 year ago

The 503A pharmacy I used lost their shortage list eligibility. Same day, compounding became illegal. Rules are real.

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u/solene_eriksen7 points·1 year ago

the shortage list is temporary, it ends and compounding becomes illegal again

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u/ffmi_watcher3 points·1 year ago

the shortage list is temporary, it ends and compounding becomes illegal again

Disagree on that part. 98.7% and 98.9% on the same vial is normal.

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u/cold_chromatogram3126 points·1 year ago

telehealth costs 503A plus compounding markup, total varies

Disagree on that part. 98.1% and 98.3% on the same vial is normal.

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u/eu_apotheke_a13 points·1 year ago

That is net peptide content, not purity. Different number, different meaning.

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About c/compounding

Compounded GLP-1s as a supply route: the 503A/503B distinction, the shortage-list mechanics that made compounding legal and then didn't, state board rules, telehealth prescriber models, and what a compounding pharmacy will and will not tell you about its API source.

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