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c/coldchain·posted 1 year ago by u/elodie_kuipers

the stability thing finally clicked for me and I want to write it down

Question Long Haul ×4 Cold Box ×3

Quick one. Canada here.

stability works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US.

Specifics: the route I used took 8 weeks and cost roughly what I expected. The admin was worse than the cost. The thing that would have saved me the most time was knowing which document to ask for at the start.

Happy to answer questions from anyone in the same jurisdiction.

1,521 up / 313 down83% upvoted39 commentsid qd45e718 Sep 2024

39 comments

9 in this archive, depth 3

best — the order this archive was captured in

u/ines_lindqvist127 points·1 year ago

stability after excursion is not zero, it is dose-dependent

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u/hamza_weiss51 points·1 year ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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u/anya_salgado18 points·1 year ago

lane reports need origin, destination, carrier, and actual transit days

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u/britt_okwuosa-3 points·1 year ago

Customs clearance took 16 days. Package sat unrefrigerated during that. Powder tested clean after, reconstituted solution probably would not have.

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u/prior_auth_painappeals1 point·1 year ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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u/bence_ibarra1 point·1 year ago

time-at-temperature integral is the dose, not just peak temperature

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u/sten_palacios46 points·1 year ago

Titration speed is a side-effect dial far more than an efficacy dial.

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u/transit_variance21 points·1 year ago

Logger trace from my shipment: 3 hours at 15°C. Powder tested 98.3% against 98.4% claim. Tolerates more than the box implies.

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About c/coldchain

Temperature and stability in the real world: what an excursion actually costs you, why lyophilised powder is far more forgiving than reconstituted solution, how to read a logger CSV, and how to photograph a failed shipment so the conversation with the vendor is short.

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