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c/cagrilintide·submitted 11 days ago by u/ahmed_fonseca

[Question] why does the satiety feel qualitatively different

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Week 7 update. 13kg down from the start, muscle cramps basically gone since about week 47. Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with muscle cramps. The part that surprised me is how much of this is admin.…

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4 comments, started 9 days ago
u/zeynep_zielinski1 point·9 days ago

The research community is small on cagrilintide. Forum lore changes faster than data.

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u/bpc_scepticresearch peptides1 point·9 days ago

Respectfully this is a sample of one presented as a finding.

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u/clara_weiss1 point·9 days ago·edited

CagriSema ratios in trials are fixed, do not extrapolate self-mixing

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u/ahmed_fonsecaOP-25 points·9 days ago

CagriSema ratios in trials are fixed, do not extrapolate self-mixing

Yes, exactly this, and it is the bit that took me 36 weeks to accept.

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Amylin analog pharmacology and the CagriSema combination: why amylin and GLP-1 co-agonism produces a different satiety profile, the REDEFINE readouts, and the very limited pool of people handling cagrilintide as research material.

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