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c/cagrilintide·posted 11 days ago by u/ahmed_fonseca

[Question] why does the satiety feel qualitatively different

Question

Week 7 update. 13kg down from the start, muscle cramps basically gone since about week 47.

Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with muscle cramps.

The part that surprised me is how much of this is admin. Ordering, storing, logging, remembering. Nobody mentions that the hard bit is not the drug, it is the routine.

Happy to answer anything. Please do not ask me what dose you should be on.

0 up / 0 down40% upvoted5 commentsid efnawj19 Jul 2026

5 comments

5 in this archive, depth 3

best — the order this archive was captured in

u/throwaway_44b12 points·10 days ago

the amylin agonist pool is small, community is satiety

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u/zeynep_zielinski1 point·9 days ago

The research community is small on cagrilintide. Forum lore changes faster than data.

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u/bpc_scepticresearch peptides1 point·9 days ago

Respectfully this is a sample of one presented as a finding.

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u/clara_weiss1 point·9 days ago·edited

CagriSema ratios in trials are fixed, do not extrapolate self-mixing

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u/ahmed_fonsecaOP-25 points·9 days ago

CagriSema ratios in trials are fixed, do not extrapolate self-mixing

Yes, exactly this, and it is the bit that took me 36 weeks to accept.

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Amylin analog pharmacology and the CagriSema combination: why amylin and GLP-1 co-agonism produces a different satiety profile, the REDEFINE readouts, and the very limited pool of people handling cagrilintide as research material.

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