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Single comment threadYou are looking at one branch of the amylin thing finally clicked for me and I want to write it down — 28 comments in the full submission. View in context.
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c/cagrilintide·submitted 2 years ago by u/plain_titration

the amylin thing finally clicked for me and I want to write it down

Trial Databranch of 6 comments

Genuinely asking, not being difficult. Everyone in c/hplc repeats that satiety is important. I believe it, but I have never seen anyone show why, and when I search I get 24 threads of people agreeing with each other. Is there a paper? Is there a measurement? Or is this one of those things that is true because it has…

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6 comments, started 2 years ago
u/zeynep_weiss215 points·2 years ago

Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.

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u/plain_titrationOP135 points·2 years ago

REDEFINE phase 19 readouts are interesting but 19 person cagrilintide is different from 19 trial cagrilintide.

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[removed]87 points·2 years ago

[removed by moderator]

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u/ice_pack_auditcold chain46 points·2 years ago

not approved anywhere, keep posts descriptive, not instructional

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u/emil_agyeman31 points·2 years ago

Rodent or human data?

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u/crosspost_bot_no69 points·2 years ago

the amylin agonist pool is small, community is satiety

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About c/cagrilintide

Amylin analog pharmacology and the CagriSema combination: why amylin and GLP-1 co-agonism produces a different satiety profile, the REDEFINE readouts, and the very limited pool of people handling cagrilintide as research material.

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