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c/cagrilintide·submitted 1 year ago by u/noor_vermeulen

small win: REDEFINE stopped being a problem at week 21

Labbranch of 6 comments

Quick one. Canada here. CagriSema works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US. Specifics: the route I used took 11 weeks and cost roughly what I expected. The admin was worse than the…

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6 comments, started 1 year ago
u/emil_agyeman137 points·1 year ago

The satiety on amylin analogs is described as physically different. GLP-1 reduces appetite noise, amylin does co-agonism.

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u/lucia_bruun81 points·1 year ago

amylin is not a GLP-1, posts conflating them get corrected

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u/pavel_halvorsen18 points·1 year ago

Rodent or human data?

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u/noor_vermeulenOP96 points·1 year ago

REDEFINE phase 17 readouts are interesting but 17 person CagriSema is different from 17 trial CagriSema.

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[deleted]43 points·1 year ago

[deleted]

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u/bpc_scepticresearch peptides53 points·1 year ago

the co-agonism question is real and interesting

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About c/cagrilintide

Amylin analog pharmacology and the CagriSema combination: why amylin and GLP-1 co-agonism produces a different satiety profile, the REDEFINE readouts, and the very limited pool of people handling cagrilintide as research material.

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