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c/cagrilintide·submitted 1 year ago by u/hedda_aguirre

three years of REDEFINE threads, summarised so you do not have to read them

Trial Databranch of 5 comments

Been lurking in c/orforglipron for about 16 months and finally have something worth posting. Short version: week 70, 12.5mg, and amylin is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 3 threads, and the answers split roughly down the middle. What I actually want to know…

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5 comments, started 1 year ago
u/ice_pack_auditcold chain23 points·1 year ago

The evidence standard in c/vendorvetting gets called too strict about once a month, and every time, the thread ends with the complainant agreeing.

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u/ms_fragmenter29 points·1 year ago

Yeah, amylin is doing different work than GLP-1.

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u/amylin_amyamylin7 points·1 year ago

CagriSema is a fixed combo in trials, not user-mixed

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u/hedda_aguirreOP3 points·1 year ago

REDEFINE phase 9 readouts are interesting but 9 person amylin is different from 9 trial amylin.

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u/rina_sobczak8 points·1 year ago

REDEFINE readouts are phase 13 data

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Amylin analog pharmacology and the CagriSema combination: why amylin and GLP-1 co-agonism produces a different satiety profile, the REDEFINE readouts, and the very limited pool of people handling cagrilintide as research material.

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