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c/cagrilintide·submitted 1 year ago by u/zeynep_weiss

[Question] how do you actually verify REDEFINE

Questionbranch of 7 comments

Been lurking in c/cryptopay for about 12 months and finally have something worth posting. Short version: week 52, 2.4mg, and REDEFINE is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 17 threads, and the answers split roughly down the middle. What I actually want to know…

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7 comments, started 1 year ago
u/tove_vasquez67 points·1 year ago

REDEFINE readouts are phase 20 data

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u/throwaway_44b133 points·1 year ago

REDEFINE readouts are phase 13 data

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u/titration_marshalmod · c/semaglutide10 points·1 year ago

the co-agonism question is real and interesting

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u/bpc_scepticresearch peptides2 points·1 year ago

the co-agonism question is real and interesting

Adding to this: REDEFINE is doing more work than the comment implies.

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u/noor_hovland32 points·1 year ago

amylin is not a GLP-1, posts conflating them get corrected

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u/elin_lundgren36 points·1 year ago

research use only, no human protocols in posts

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u/zeynep_weissOP97 points·1 year ago

REDEFINE readouts are phase 20 data

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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Amylin analog pharmacology and the CagriSema combination: why amylin and GLP-1 co-agonism produces a different satiety profile, the REDEFINE readouts, and the very limited pool of people handling cagrilintide as research material.

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