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c/cagrilintide·submitted 1 year ago by u/helga_vermeulen

the CagriSema question that gets asked weekly, answered properly

Questionbranch of 4 comments

co-agonism. That is the whole post, but I will justify it. Everything else people worry about in c/labresults is downstream of it. Titration speed, muscle cramps, the endless dose arguments — most of it resolves if you sort co-agonism out first, and almost nobody does. I say this having got it wrong for 9 months. My…

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4 comments, started 1 year ago
u/b12_baseline51 points·1 year ago·edited

the co-agonism question is real and interesting

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u/amara_halonen17 points·1 year ago

Strongly agree. REDEFINE is phase 10, not final.

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[removed]8 points·1 year ago

[removed by moderator]

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u/b12_baseline2 points·1 year ago

That is net peptide content, not purity. Different number, different meaning.

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Amylin analog pharmacology and the CagriSema combination: why amylin and GLP-1 co-agonism produces a different satiety profile, the REDEFINE readouts, and the very limited pool of people handling cagrilintide as research material.

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