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c/bpc157·submitted 5 months ago by u/arne_ilunga

[Question] how do you actually verify rodent data

Questionbranch of 4 comments

Confession thread, sort of. I went from 5mg to 1.7mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 19 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway. So now I have muscle cramps…

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4 comments, started 5 months ago
u/clara_danquah10 points·5 months ago

Titration speed is a side-effect dial far more than an efficacy dial.

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u/dose_diary_danalog keeper12 points·5 months ago

Yeah, rodent data does not scale to humans.

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u/vikram_mbeki14 points·4 months ago

Did anything else change in the same window?

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u/hamza_weiss7 points·4 months ago

near-zero controlled human data, full stop

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BPC-157 as it actually is: a pentadecapeptide with a genuinely interesting rodent tendon-and-gut literature, near-zero controlled human data, a naming and sequence mess in the supply chain, and a regulatory status that changed sharply in several countries.

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