stalled for 8 weeks at 12.5mg and I refuse to panic this time
eGFR. That is the whole post, but I will justify it.
Everything else people worry about in c/orforglipron is downstream of it. Titration speed, reflux, the endless dose arguments — most of it resolves if you sort eGFR out first, and almost nobody does.
I say this having got it wrong for 2 months. My fasting insulin was the thing that eventually made me pay attention, which is a stupid way to learn a lesson that was in the sidebar the whole time.
best — the order this archive was captured in
Respectfully this is a sample of one presented as a finding.
Yeah, baseline matters more than any later number.
Do you have baseline to compare to?
nobody here can tell you what a result means for you
Strongly agree. ALT is where you catch the liver story early.
This is correct. ApoB is the better marker.
baseline is the most important eGFR measurement, you cannot collect it later
eGFR noise during rapid loss is expected
Ferritin tanked from 4 to 36. Small appetite, reduced iron intake, nobody was testing it until I asked.
HOMA-IR is crude but free and useful for tracking
eGFR noise during rapid loss is expected
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
[removed by moderator]
eGFR from 20 to 22 is movement, not noise
This is the "correlation is mechanism" thing again. You changed three variables at once.
Baseline ferritin: 97.6. Week 77: 98.0. Same lab, fasted, same time of day. Trend matters.
Tracking number removed. It identifies both ends of a shipment.
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
A1c moves slowly, quarterly is plenty
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
Small correction: the trial was 18 weeks, not 28. Does not change your point but people will quote it.
This is correct. ApoB is the better marker.
redact identifying details from lab PDFs before posting
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
A1c moves slowly, quarterly is plenty
- 1Baseline ferritin: 97.6. Week 77: 98.0. Same lab, fasted, same time of day.…10 comments in this branch · started by u/micro_bump_mick
- 2Respectfully this is a sample of one presented as a finding.8 comments in this branch · started by u/kofi_balogun