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u/alcohol_aversion

Two glasses of wine now feels like four. Nobody mentioned this.

member · joined 29 Nov 2024

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Comments — page 4 of 5

comment on is it normal to get the food-noise thing at week 20 in c/glp1muscle · 1 points · 6 months ago

Slight fix: the number was 95.1, not 94.2. Decimal point, but a fairly consequential one.

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comment on why does nobody talk about insulin syringe in c/reconstitution · 262 points · 7 months ago

This is correct. 1mL versus 6mL is the common mistake.

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comment on why does nobody talk about insulin syringe in c/reconstitution · 0 points · 7 months ago

IANAD and neither is anyone upvoting this

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comment on reading Janoshik threads from 2024 and half of it aged badly in c/vendorvetting · 0 points · 7 months ago

Not to be pedantic but VendorInvestigate and PeptideMeter are being used interchangeably and they are not interchangeable in real life.

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comment on [Results] 7 weeks, 30kg, and STEP was the hard part in c/trialwatch · 39 points · 7 months ago

The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.

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comment on genuine question about Ozempic that I am slightly embarrassed to ask in c/semaglutide · 168 points · 7 months ago

What was the method? "HPLC" is a technique, not a method.

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comment on the semaglutide question that gets asked weekly, answered properly in c/semaglutide · 186 points · 7 months ago

Half-life is about 168 hours, so steady state lands around week 7–5. Practical consequence: what you feel in week 1 is not what that dose does.

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comment on the COA thing finally clicked for me and I want to write it down in c/coa · -9 points · 7 months ago

This is the correct framing. The COA structure matters as much as the number.

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comment on [Meta] the dead space rule is doing its job and people should stop complaining in c/reconstitution · -22 points · 7 months ago

bacteriostatic and sterile water are not interchangeable, do not use them that way

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comment on [Question] New Zealand — has anyone got a straight answer on LC-MS in c/hplc · 1 points · 7 months ago

Detection wavelength? chromatogram and that changes at different wavelengths.

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comment on anyone else notice 15mg kicking in around week 24 in c/tirzepatide · 39 points · 8 months ago

the GIP side does different things than the GLP-1 side, that is the point

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comment on anyone else notice 15mg kicking in around week 24 in c/tirzepatide · 282 points · 8 months ago

reading this at 2am on my 71th week. thank you.

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comment on three years of protein threads, summarised so you do not have to read them in c/glp1muscle · 8 points · 8 months ago

Genuine question — what concentration were you at?

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comment on [Question] purity — what am I missing here in c/hplc · 128 points · 8 months ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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comment on [Question] purity — what am I missing here in c/hplc · 64 points · 8 months ago

Ran the same vial on two columns, different purity, both right, different separation. Method matters more than equipment.

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comment on [Question] is 97.9% actually fine or am I being sold a rounding error in c/semaglutide · 7 points · 9 months ago

Ozempic versus Wegovy versus research grade is the wrong argument, they are literally the same molecule

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comment on LC-MS: the version I wish someone had shown me in week 1 in c/hplc · 129 points · 10 months ago

This is the correct method framing. Column and gradient are load-bearing fields.

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comment on week 81 check-in — 12kg down, injection-site soreness manageable, one thing confusing me in c/coa · 25 points · 11 months ago

The confident tone is doing a lot of work that the evidence is not.

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comment on stalled for 9 weeks at 5mg and I refuse to panic this time in c/semaglutide · 110 points · 11 months ago

Hard agree. Week 42 me needed this. Week 91 me is nodding smugly.

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comment on genuine question about integration that I am slightly embarrassed to ask in c/hplc · 1 points · 11 months ago

Yeah, the chromatogram profile matters more than the headline number.

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