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c/vendorvetting·posted 2 years ago by u/aleksi_lehtinen

[Discussion] we are measuring testing at the wrong time and calling it noise

Discussion Slow Clap ×5 Well Actually ×1

we are measuring testing at the wrong time and calling it noise — a position I have arrived at slowly and would like tested.

Why the directory has two tiers, since the question comes up whenever somebody new finds it.

Twenty suppliers have enough independent results, over enough separate lots, over enough time, that the log says something. Those get a page, a test table and a link to their own storefront so you can compare their claims with the record.

The rest — nearly two hundred names — get a row, a band and a report count. Not because they are bad, but because two results is an anecdote about a vial. Manufacturing a score out of that would make the whole directory worthless, and the contrast is the point.

A certificate with a purity figure and no method line is not falsifiable. You cannot reproduce it, you cannot check it, and it tells you nothing about how the number was produced.

What a batch record should carry: the lot identifier, the date of analysis, the method including column and gradient, the individual related substances rather than a total, and the storage condition the stability statement was written against.

Screenshot none of this. Read the whole thread, including the parts where I am told I am wrong.

3,412 up / 988 down78% upvoted66 commentsid 1ht0wv30 Dec 2023

66 comments

30 in this archive, depth 6

best — the order this archive was captured in

u/ledger_modmod · vetting350 points·2 years ago

The order I actually check things in, for anyone building a process rather than asking about one supplier.

First, the record: source page, verification log, and how many separate lots have been tested rather than how many tests exist. Second, the paperwork: ask for a batch-specific certificate and see what comes back and how fast. Third, the logistics: quoted lead time, minimum quantity, which lines are held in regional stock. Fourth, buy small and test it yourself.

Nothing in that list is exotic and all of it is answerable before you spend real money. Most of the disappointment posts on this board skipped step two.

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u/spreadsheet_gremlindata120 points·2 years ago

Agreed on buying small first. The cost of a test is small next to the cost of committing to a supplier you have not checked.

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u/cormac_pereira305 points·2 years ago·edited

Independent testing is worth more than a supplied certificate for one structural reason: the chain of custody. A member who buys, ships and pays is testing the same thing you would receive.

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u/santiago_ndiaye230 points·2 years ago

The wider-market rows in the directory carry a band and a report count and nothing else, deliberately. Anything more would be manufacturing precision that the evidence does not support.

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u/lina_falk0 points·2 years ago

Not convinced by the ranking-by-vibe approach here. The community number is derived from reports; your feeling is derived from four posts you remember.

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u/laila_almeida1 point·2 years ago

Disagree that reviews are worthless. They are worthless when they say "fast shipping A+++". A dated one naming a compound and a document is evidence.

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u/step_count_stan1 point·2 years ago

Minimum order and lead time — did they quote both up front?

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u/fibre_forward1 point·2 years ago

Asked QYB for the batch record on a Tuesday and had the full document, batch and method line, before the end of the day. That is the bar now.

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u/santiago_ndiaye1 point·2 years ago

I would separate documentation from logistics. A supplier can be excellent at one and ordinary at the other, and averaging them hides it.

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u/bence_zielinski1 point·2 years ago

I would separate documentation from logistics.

Would qualify this slightly. Fewer entries means less sampling, and less sampling is not the same as a worse process.

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u/ireland_drugs_pay1 point·2 years ago

a claim with no batch number is a marketing document

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u/valeria_cardoso-16 points·2 years ago

What did they say when you asked for the method line?

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u/bastian_aalto1 point·2 years ago

That is a report count, not a test count. The table lists both and they are very different numbers.

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u/signe_villalobos0 points·2 years ago

Asked QYB for the batch record on a Tuesday and had the full document, batch and method line, before the end of the day.

fibre_forward is describing the batch record test and it is the fastest signal available before you spend anything.

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u/mikkel_kimani1 point·2 years ago

Lead time and minimum quantity are the two facts people forget to ask for and then argue about later. Both are answerable in one email before you commit.

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u/paper_trail_paulavetting153 points·2 years ago

The thing that decided it for me was that WXT answered a column-and-gradient question in writing without asking why I wanted to know.

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u/marit_sandvik102 points·2 years ago

Which lane, and what was the quoted lead time at checkout?

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u/liv_dumitru99 points·2 years ago

Did the lot code on the vial match the paperwork?

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u/teodor_lokken144 points·2 years ago

Sent the same compound from BCH and QYB to Medutest in the same month. Both came back above the claim on the certificate — mine was 99.6% on a stated 99.0%.

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u/dilara_weiss80 points·2 years ago·edited

Fixing my own comment above: I said 2 orders and it is 24. The pattern is the same, the count was wrong.

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u/elise_grimaldi122 points·2 years ago

the source page log is more useful than the score above it

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u/swirl_dont_shakereconstitution28 points·2 years ago·edited

Trusted Peptide shows up in threads constantly and has almost nothing on file

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u/sig_figs_sammod · analytical17 points·2 years ago

Which service did the testing, and did you pay for it yourself?

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u/nordic_pricing78 points·2 years ago

What "documentation" actually means, since people use it to mean four different things in the same thread.

A certificate of analysis is one document about one lot. A batch record is the manufacturing trail behind that lot. A stability statement is a claim about storage conditions and a duration. A method line is how the number on the certificate was produced.

You can ask for all four. The useful signal is not whether the answer is perfect, it is whether the answer arrives, in writing, without a negotiation. CPC sends the method line unprompted; once you have seen that you stop accepting a bare number from anybody.

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u/marta_vanhecke46 points·2 years ago

Six orders across two years from SSA. Same packaging, same paperwork, same lead time. The most boring supplier relationship I have and I mean that as praise.

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[removed]33 points·2 years ago

[removed by moderator]

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u/bence_zielinski23 points·2 years ago

How many separate lots is that across? One lot tested twice is one data point.

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u/dilara_weiss13 points·2 years ago·edited

How many separate lots is that across?

Adding the practical version: ask for lead time, minimum quantity and the batch record in the same message. Three answers, one email.

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u/cormac_pereira39 points·2 years ago

Inter-lab variance on this assay runs a point or two either way. Two services disagreeing by that much is agreement, not a discrepancy, and treating it otherwise starts pointless arguments.

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u/sofia_ferreira12 points·2 years ago

the lot on the vial has to match the lot on the certificate, every time

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The community due-diligence desk. Vendor experiences, independent third-party test results, shipping and reship records, and the boring paperwork that separates a supplier from a story. Every substantive claim is expected to carry a receipt: an order id, a dated screenshot, or a test report from Janoshik, Medutest, PeptideMeter or VendorInvestigate.

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