[Trial Data] STEP 1 vs SURMOUNT-1 side by side, with the caveats
Week 22 update. 43kg down from the start, reflux basically gone since about week 62. Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with reflux. The part that surprised me is how much of this is admin. Ordering,…
Disagree but this is the good kind of wrong — it is specific enough to be checked.
This is correct. Discontinuation arms show the regain reality.
phase 2 is not phase 3, smaller n and shorter trial
the discontinuation arms are the interesting part, not the endpoint endpoints
the relative risk reduction in headlines is not the whole story
event rates are more informative than hazard ratios alone