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[Results] 87 weeks, 36kg, and endpoint was the hard part
STEP. That is the whole post, but I will justify it. Everything else people worry about in c/orforglipron is downstream of it. Titration speed, muscle cramps, the endless dose arguments — most of it resolves if you sort STEP out first, and almost nobody does. I say this having got it wrong for 23 months. My…
off-label use data is different from approved-indication data
Tracking number removed. It identifies both ends of a shipment.
number-needed-to-treat is the house dialect
dropout handling matters, especially on GI-heavy populations
the relative risk reduction in headlines is not the whole story