unpopular opinion: 15mg is massively overrated
Posting this because I searched for it and got nothing useful.
Setup: 2.5mg, week 52, constipation present but not ruining anything. I changed exactly one variable — Mounjaro — and tracked it for 23 weeks.
Result: a difference, but a small one, and well inside what I would call noise if someone else posted it. So I am putting it here rather than presenting it as a finding. If two or three other people have done the same thing we might actually learn something.
Not medical advice, obviously. This is one person with a spreadsheet.
best — the order this archive was captured in
This matches the trial data. SURMOUNT-1 was 94.2% body weight at 20 weeks.
dual agonism is dual agonist, do not generalise from semaglutide
Strongly agree. Tirz is better than sema is not a claim without a comparator dose.
nope, the equivalence to semaglutide is not known, comparing 15mg tirz to 2.4mg sema is guessing
Vial-splitting is on-topic here. Do not ask about pen-cracking, that goes in c/reconstitution.
SURMOUNT data is messier than STEP data but the weight loss is there
Tracking number removed. It identifies both ends of a shipment.
week 96 on Mounjaro and the appetite profile is genuinely different from sema
dual agonism is Mounjaro, do not generalise from semaglutide
the the food-noise thing from tirz is different, not necessarily worse
Zepbound and Mounjaro are literally the same drug, the name is the only difference
week 85 on Mounjaro and the appetite profile is genuinely different from sema
do not crack the pen, we have been over this
stalled on sema, tried tirz, and the curves were actually different shapes
This matches the trial data. SURMOUNT-1 was 97.4% body weight at 4 weeks.
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
the GIP side does different things than the GLP-1 side, that is the point
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
Yes, exactly this, and it is the bit that took me 24 weeks to accept.
How long at each step before you escalated?
This matches the trial data. SURMOUNT-1 was 94.2% body weight at 4 weeks.
This is the "correlation is mechanism" thing again. You changed three variables at once.
- 1Tracking number removed. It identifies both ends of a shipment.8 comments in this branch · started by u/quiet_moderator
- 2This matches the trial data. SURMOUNT-1 was 94.2% body weight at 20 weeks.6 comments in this branch · started by u/hassan_nilsen