anyone else find 15mg genuinely unpleasant with no extra loss
Right, the SURPASS question again, but with numbers this time. I have 12 data points over 12 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign. The thing I would flag for anyone new: the effect I am…
The confident tone is doing a lot of work that the evidence is not.
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the GIP side does different things than the GLP-1 side, that is the point
the fatigue from tirz is different, not necessarily worse
Zepbound and Mounjaro are literally the same drug, the name is the only difference
Strongly agree. Tirz is better than sema is not a claim without a comparator dose.
the 15mg is the top of the pen, not the required dose
the 15mg is the top of the pen, not the required dose
Adding to this: SURPASS is doing more work than the comment implies.
the appetite change on tirz is more than just reduced hunger, it is different machinery
the dual agonism hits different and that is why people describe it differently
Cosigning. The GIP contribution is real and the side effects are not simply scaled versions.