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c/tirzepatide·submitted 1 year ago by u/nz_unfunded

[Meta] the SURMOUNT rule is doing its job and people should stop complaining

Discussionbranch of 6 comments

Been lurking in c/compounding for about 13 months and finally have something worth posting. Short version: week 29, 0.5mg, and GIP is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 13 threads, and the answers split roughly down the middle. What I actually want to know is…

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6 comments, started 1 year ago
u/emil_barros0 points·1 year ago

The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.

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u/quiet_moderatormod1 point·1 year ago

Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.

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u/amara_halonen1 point·1 year ago

the nausea from tirz is different, not necessarily worse

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u/ferritin_low1 point·1 year ago

nope, the equivalence to semaglutide is not known, comparing 15mg tirz to 2.4mg sema is guessing

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u/nz_unfundedOP1 point·1 year ago

Vial-splitting is on-topic here. Do not ask about pen-cracking, that goes in c/reconstitution.

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[deleted]1 point·1 year ago

[deleted]

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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