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c/tirzepatide·submitted 5 months ago by u/crosspost_bot_no

what changed for me between week 65 and week 19

Labbranch of 6 comments

Been lurking in c/compounding for about 24 months and finally have something worth posting. Short version: week 80, 7.5mg, and GIP is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 7 threads, and the answers split roughly down the middle. What I actually want to know is…

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6 comments, started 4 months ago
u/dexa_twice_yearlybody comp-19 points·4 months ago

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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u/neha_falk1 point·4 months ago·edited

What was the trial arm you are quoting from? SURMOUNT-1, -2, -3 are all different.

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u/titration_marshalmod · c/semaglutide1 point·4 months ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/rania_marchand1 point·4 months ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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u/crosspost_bot_noOP1 point·4 months ago

This matches the trial data. SURMOUNT-1 was 94.2% body weight at 8 weeks.

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[removed]1 point·4 months ago

[removed by moderator]

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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