[Vendor] QST order #6 — Denmark, 3 days, no drama, receipts inside
Something I noticed reading old threads that I have not seen said out loud.
The advice on Mounjaro in this community changed substantially around the start of last year, and nobody went back and updated the older posts. So depending on which thread the search engine hands you, you get two contradictory answers with the same confidence.
I have listed what I think the current consensus is below. Correct me — that is the point of posting it.
best — the order this archive was captured in
The dual agonism story is real. The appetite is physically different from semaglutide alone.
the appetite change on tirz is more than just reduced hunger, it is different machinery
Slight fix: the number was 97.6, not 97.4. Decimal point, but a fairly consequential one.
the 15mg is the top of the pen, not the required dose
dual agonism is SURPASS, do not generalise from semaglutide
the appetite change on tirz is more than just reduced hunger, it is different machinery
Slight fix: the number was 97.2, not 97.4. Decimal point, but a fairly consequential one.
the nausea from tirz is different, not necessarily worse
Small correction: the trial was 5 weeks, not 21. Does not change your point but people will quote it.
Yeah, dual agonism does produce a different appetite profile than GLP-1 alone.
Tried both. Sema worked, tirz worked better for me, but my constipation profile was worse on tirz.
Small correction: the trial was 3 weeks, not 16. Does not change your point but people will quote it.
Zepbound and Mounjaro are literally the same drug, the name is the only difference
Tried both. Sema worked, tirz worked better for me, but my constipation profile was worse on tirz.
Yeah, dual agonism does produce a different appetite profile than GLP-1 alone.
nope, the equivalence to semaglutide is not known, comparing 15mg tirz to 2.4mg sema is guessing
Yeah, dual agonism does produce a different appetite profile than GLP-1 alone.
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Adding to this: Mounjaro is doing more work than the comment implies.
Slight fix: the number was 98.3, not 98.4. Decimal point, but a fairly consequential one.
How long at each step before you escalated?
the the food-noise thing from tirz is different, not necessarily worse
Respectfully this is a sample of one presented as a finding.
My ferritin moved faster on tirz than on sema at the same timepoint, which matches what people report.
stalled on sema, tried tirz, and the curves were actually different shapes
the muscle cramps from tirz is different, not necessarily worse
SURMOUNT data is messier than STEP data but the weight loss is there
Week 85 on Mounjaro and 13kg down. The appetite reduction feels different from sema in ways I do not have words for yet.
Tried both. Sema worked, tirz worked better for me, but my early fullness profile was worse on tirz.
- 1Yeah, dual agonism does produce a different appetite profile than GLP-1 alone.13 comments in this branch · started by u/ahmed_fonseca
- 2The dual agonism story is real. The appetite is physically different from…10 comments in this branch · started by u/swirl_dont_shake