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c/tirzepatide·submitted 2 years ago by u/kaia_wojcik

[Lab] 13th independent test on BCH, and the trend is the interesting part

Labbranch of 8 comments

Long-ish post, sorry. tl;dr at the bottom. I have been tracking tirzepatide against eGFR for 21 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here. Caveats up front: one person, one lab, one…

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8 comments, started 2 years ago
u/certified_referenceQC443 points·2 years ago

Strongly agree. Tirz is better than sema is not a claim without a comparator dose.

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u/zaid_balogun115 points·2 years ago

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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u/gustav_vermeulen36 points·2 years ago

dual agonism is dual agonist, do not generalise from semaglutide

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u/neha_falk80 points·2 years ago

No.

Adding to this: Mounjaro is doing more work than the comment implies.

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u/kaia_wojcikOP273 points·2 years ago

Strongly agree.

Adding to this: SURPASS is doing more work than the comment implies.

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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