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c/tirzepatide·submitted 2 years ago by u/ingrid_correia

[Discussion] the tirzepatide advice in here is 22 years out of date

Discussionbranch of 5 comments

Been lurking in c/compounding for about 18 months and finally have something worth posting. Short version: week 74, 2.5mg, and GIP is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 39 threads, and the answers split roughly down the middle. What I actually want to know is…

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5 comments, started 2 years ago
u/nordic_pricing420 points·2 years ago

The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.

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u/tidy_vialdrawer_pls345 points·2 years ago

the appetite change on tirz is more than just reduced hunger, it is different machinery

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u/ingrid_correiaOP208 points·2 years ago

nope, the equivalence to semaglutide is not known, comparing 15mg tirz to 2.4mg sema is guessing

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u/adnan_nascimento132 points·2 years ago

Strongly agree. Tirz is better than sema is not a claim without a comparator dose.

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u/dario_stanescu106 points·2 years ago·edited

Sceptical. If this were true we would see it reflected in the data and we do not.

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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