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c/sideeffects·posted 11 months ago by u/liv_okafor

[Discussion] the gallbladder advice in here is 17 years out of date

Discussion Clean Column ×5 Sourced ×1

I have had 20 orders now and I keep a table, so here is the honest summary rather than a vibe.

Material has been consistent. Communication has not. Shipping has varied by about 24 days on nominally the same lane, which matters more in summer than in February.

The independent number came back 98.4% against a claimed 98.6%, which I read as agreement rather than a discrepancy — inter-lab variance on this assay is a point or two either way and treating one lab as ground truth is how people end up in pointless arguments with vendors.

Batch number is in the comments. Ask if you want the method.

2,769 up / 659 down81% upvoted65 commentsid h2us1m16 Aug 2025

65 comments

30 in this archive, depth 6

best — the order this archive was captured in

u/coring_the_stopper286 points·11 months ago

hair loss is real and usually reversible when you stabilize

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[deleted]213 points·11 months ago

[deleted]

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u/laila_delgado148 points·11 months ago

[deleted]

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/aurel_mwangi61 points·11 months ago

nausea on day 2 is normal, nausea after week 92 is worth checking

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u/placebo_arm_pam244 points·11 months ago

Yeah, the constipation hit on day 20 for me too, not day 1.

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u/zeynep_zielinski194 points·11 months ago·edited

IANAD and neither is anyone upvoting this

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u/usp_appendixcompendial0 points·11 months ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/blunt_coldbox_202483 points·11 months ago

Slight fix: the number was 98.7, not 99.3. Decimal point, but a fairly consequential one.

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u/ipamorelin_i-23 points·11 months ago

Not to be pedantic but gallbladder and heart rate are being used interchangeably and they are not interchangeable in real life.

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u/ferran_dahlberg64 points·11 months ago

Slight fix: the number was 98.7, not 99.3.

Adding to this: constipation is doing more work than the comment implies.

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u/liv_okaforOP29 points·11 months ago

sulphur burps are disgusting but not dangerous, 23 weeks and they stopped

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u/insulin_syringe_ian114 points·11 months ago

The evidence standard in c/vendorvetting gets called too strict about once a month, and every time, the thread ends with the complainant agreeing.

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u/constipation_clubMOD87 points·11 months ago

Removed a chain here. The rule is one line long and it is not negotiable.

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u/graph_it_gary72 points·11 months ago

Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.

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u/wrong_network_w22 points·11 months ago·edited

week 15 and the nausea is finally getting better

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u/clara_weiss6 points·11 months ago

week 92 and the nausea is finally getting better

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u/liv_okaforOP63 points·11 months ago

Resting heart rate up 8 bpm from baseline, settled back down once I stopped escalating. Tracked daily so I am confident.

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u/sofia_wikstrom66 points·11 months ago

Same experience. Week 2 and it simply stopped. I know that is not useful information but it is what happened.

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u/step_therapy_s25 points·11 months ago

resting heart rate moved up 22 bpm and settled back down when I stopped escalating

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u/liv_okaforOP28 points·11 months ago

Strongly agree. Describe your dose, your week number, and your titration speed or nobody can help.

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u/iman_falk7 points·11 months ago

the food-noise thing stops around week 54 for most people

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u/hassan_castellanos2 points·11 months ago

nausea on day 2 is normal, nausea after week 3 is worth checking

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u/usp_appendixcompendial1 point·11 months ago

the muscle cramps passes. i promise. not medical advice.

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u/leila_silva1 point·11 months ago

week 89 and the fatigue is finally getting better

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u/vendorinvestigate_vic35 points·11 months ago

hair loss is real and usually reversible when you stabilize

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u/adaeze_brandt32 points·11 months ago

the sulphur burps passes. i promise. not medical advice.

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u/milan_villalobos23 points·11 months ago

Went to A&E convinced it was pancreatitis. Lipase normal. It was gallstones. Get checked, do not post and wait.

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About c/sideeffects

Side-effect experience and management, with a strong bias toward the ones that are common and boring (nausea, constipation, reflux, fatigue, sulphur burps) and a hard line on the ones that are not (severe abdominal pain, persistent vomiting, jaundice, vision changes). This community is not a substitute for urgent care and the mods will say so bluntly.

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