c/sideeffects wiki

What this community is for

Side-effect experience and management, with a strong bias toward the ones that are common and boring (nausea, constipation, reflux, fatigue, sulphur burps) and a hard line on the ones that are not (severe abdominal pain, persistent vomiting, jaundice, vision changes). This community is not a substitute for urgent care and the mods will say so bluntly.

c/sideeffects was created on 22 Aug 2023 and currently has 118,600 members and 130 captured submissions. It sits in the busiest tier of the site, which mostly affects how fast a question gets answered rather than how well.

Rules, and why each exists

Community rules come first, then the six site-wide rules that apply everywhere on GLP Research Hub. Community rules are enforced by the moderators listed at the bottom of this page; site rules are enforced by everyone.

1. Severe or escalating abdominal pain is an urgent-care question, not a forum question. We will lock those threads with a pointer to help.
2. Describe your dose, your week number and your titration speed — otherwise nobody can help.
3. No diagnosing strangers. Share what happened to you.

And the site rules, which are short on purpose:

1. Independent community. Nobody here sells anything, and anyone who tries is banned.
2. Not medical advice. Describe what you did; never prescribe to a stranger.
3. Claims need evidence. Batch numbers, dated screenshots, independent test reports, or a citation.
4. No referral links, discount codes or affiliate URLs. Permanent ban, no appeal.
5. No contact handles, wallet addresses or tracking numbers — they identify people.
6. Be recognisably decent. Disagree hard, insult nobody.

Terms you will see

Vocabulary that turns up constantly in c/sideeffects. Each links to the topic page, which collects every submission that touches it.

• nausea — discussed frequently in this community — see the topic page for every submission that touches it.
• constipation — discussed frequently in this community — see the topic page for every submission that touches it.
• reflux — discussed frequently in this community — see the topic page for every submission that touches it.
• fatigue — discussed frequently in this community — see the topic page for every submission that touches it.
• hair loss — discussed frequently in this community — see the topic page for every submission that touches it.
• sulphur burps — discussed frequently in this community — see the topic page for every submission that touches it.
• gallbladder — discussed frequently in this community — see the topic page for every submission that touches it.
• heart rate — discussed frequently in this community — see the topic page for every submission that touches it.

Start here

The twelve highest-scoring submissions in this community. Not necessarily the most correct — the most agreed-with, which is a different thing, and worth remembering when you read them.

1. stalled for 4 weeks at 2.4mg and I refuse to panic this time — 11k points, 51 comments, 1 year ago
2. what changed for me between week 75 and week 23 — 10k points, 60 comments, 2 years ago
3. [Results] 32 weeks, 11kg, and gallbladder was the hard part — 9.7k points, 66 comments, 2 years ago
4. switched from 7.5mg to 15mg and the injection-site soreness got better, not worse — 8.5k points, 49 comments, 2 years ago
5. anyone else notice nausea kicking in around week 60 — 8.1k points, 35 comments, 2 years ago
6. gallbladder vs fatigue — genuinely asking which matters more — 7.9k points, 33 comments, 2 years ago
7. why does nobody talk about heart rate — 7.2k points, 42 comments, 2 years ago
8. [Vendor] WXT order #14 — France, 7 days, no drama, receipts inside — 7.1k points, 57 comments, 1 year ago
9. [Meta] proposal — a flair for hair loss posts — 7k points, 53 comments, 2 years ago
10. stalled for 8 weeks at 2.4mg and I refuse to panic this time — 6.8k points, 64 comments, 1 year ago
11. hair loss — my 20-week log, condensed into one table — 6.8k points, 42 comments, 2 years ago
12. week 41 check-in — 22kg down, muscle cramps manageable, one thing confusing me — 6.7k points, 53 comments, 2 years ago

Asked constantly

• [Question] resting heart rate up 7bpm, week 6, is that a thing
• muscle cramps turned out to be sodium, not magnesium
• [PSA] dizzy on standing? check whether your BP meds are now too strong
• sulphur burps: a taxonomy, a timeline, and my sincere apologies to my flatmate
• anyone else notice gallbladder kicking in around week 39
• [Lab] SGN reta — VendorInvestigate came back 93.7% against a claimed 94.2%
• [Question] Ireland — has anyone got a straight answer on sulphur burps
• [Question] New Zealand — has anyone got a straight answer on constipation
• unpopular opinion: gallbladder is massively overrated
• anyone else notice gallbladder kicking in around week 49

If your question is on that list, read the answers there first. If it is not, ask it — that is what the community is for, and "this has been asked" is only a helpful reply when it comes with a link.

Who runs this

Moderation here is done by volunteers who also post as normal members. They are not clinicians, not vendors, and not paid.

• u/nausea_notes — Nausea log, 14 months, what helped and what was placebo. Ginger did nothing for me.
• u/constipation_club — Magnesium, fibre timing, hydration, movement. In that order of impact for me.
• u/quiet_moderator — I remove the obvious stuff so you never see it. Message the modmail, not me.
• u/gentle_correction — You can be right without being unkind. Usually.