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c/sideeffects·posted 1 year ago by u/elin_lundgren

reading nausea threads from 2024 and half of it aged badly

PSA Long Haul ×6 Slow Clap ×2

nausea. That is the whole post, but I will justify it.

Everything else people worry about in c/bpc157 is downstream of it. Titration speed, early fullness, the endless dose arguments — most of it resolves if you sort nausea out first, and almost nobody does.

I say this having got it wrong for 20 months. My eGFR was the thing that eventually made me pay attention, which is a stupid way to learn a lesson that was in the sidebar the whole time.

12,476 up / 11,006 down53% upvoted39 commentsid g9dy2c30 Apr 2025

39 comments

30 in this archive, depth 5

best — the order this archive was captured in

u/sequence_checkerresearch peptides316 points·1 year ago·edited

Same experience. Week 66 and it simply stopped. I know that is not useful information but it is what happened.

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u/baseline_drifteranalytical164 points·1 year ago

Yeah, the muscle cramps hit on day 13 for me too, not day 1.

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u/elin_lundgrenOP193 points·1 year ago

constipation is real, boring, and fixable

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u/sanne_laurent131 points·1 year ago·edited

week 32 and the nausea is finally getting better

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u/hassan_castellanos155 points·1 year ago

nausea on day 2 is normal, nausea after week 60 is worth checking

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[removed]144 points·1 year ago

[removed by moderator]

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u/signe_villalobos209 points·1 year ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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u/ferran_krastev122 points·1 year ago

the food-noise thing stops around week 5 for most people

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u/zaid_balogun85 points·1 year ago

Not convinced. The evidence does not support that reading.

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u/nabila_ogunleye35 points·1 year ago

hair loss is real and usually reversible when you stabilize

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u/yannick_barros-16 points·1 year ago

resting heart rate moved up 4 bpm and settled back down when I stopped escalating

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u/usp_appendixcompendial1 point·1 year ago

Not convinced. The evidence does not support that reading.

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u/nabila_ogunleye110 points·1 year ago
appreciate you saying you do not know
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u/elin_lundgrenOP68 points·1 year ago

Resting heart rate up 11 bpm from baseline, settled back down once I stopped escalating. Tracked daily so I am confident.

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u/signe_villalobos47 points·1 year ago

ask your actual doctor, not us

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u/adnan_karlsen38 points·1 year ago

IANAD and neither is anyone upvoting this

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u/clara_weiss39 points·1 year ago

ask your actual doctor, not us

Adding to this: nausea is doing more work than the comment implies.

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u/hassan_castellanos23 points·1 year ago

Did the constipation start before or after the dose increase?

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u/piotr_bruun97 points·1 year ago

Crossposting this to c/glp1canada because the people who need it are not reading this community.

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u/baseline_drifteranalytical40 points·1 year ago

Resting heart rate up 12 bpm from baseline, settled back down once I stopped escalating. Tracked daily so I am confident.

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u/quiet_moderatorMOD65 points·1 year ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/elin_lundgrenOP52 points·1 year ago

the fatigue passes. i promise. not medical advice.

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u/marit_coelho18 points·1 year ago

severe abdominal pain is an urgent-care question, not a forum question

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u/chidi_abubakar40 points·1 year ago

This is correct. The early fullness is horrible for three weeks and then just ends.

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u/lina_dziedzic20 points·1 year ago

Strongly agree. Describe your dose, your week number, and your titration speed or nobody can help.

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u/elin_lundgren21 points·1 year ago

Disagree. What you are describing is consistent with reflux, not with what you concluded.

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u/zaid_balogun11 points·1 year ago

Disagree.

Yes, exactly this, and it is the bit that took me 87 weeks to accept.

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u/naomi_erdogan14 points·1 year ago

severe abdominal pain is an urgent-care question, not a forum question

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u/mass_spec_maggieMS4 points·1 year ago

severe abdominal pain is an urgent-care question, not a forum question

Disagree on that part. 98.1% and 98.4% on the same vial is normal.

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About c/sideeffects

Side-effect experience and management, with a strong bias toward the ones that are common and boring (nausea, constipation, reflux, fatigue, sulphur burps) and a hard line on the ones that are not (severe abdominal pain, persistent vomiting, jaundice, vision changes). This community is not a substitute for urgent care and the mods will say so bluntly.

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