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c/semaglutide·submitted 9 months ago by u/chidi_demir

week 56 check-in — 31kg down, muscle cramps manageable, one thing confusing me

Questionbranch of 6 comments

Confession thread, sort of. I went from 2.5mg to 1.0mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 9 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway. So now I have constipation…

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6 comments, started 9 months ago
u/source_or_silence369 points·9 months ago

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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u/test_it_yourselfvetting431 points·9 months ago

okay but what dose of sema are you on

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u/rina_bergstrom119 points·9 months ago

nope, 0.25 counts, it is just not the dose most people stay on

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u/careful_gradient_again76 points·9 months ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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u/kenji_vasquez64 points·9 months ago

Sceptical.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/tomas_kimani45 points·9 months ago

week 94 on the pen, 17kg down, this is the answer

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