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c/semaglutide·posted 1 year ago by u/gustav_solberg

[Results] 46 weeks on 1.0mg, full numbers, ask me anything boring

Results Clean Column ×3 Long Haul ×2 Sourced ×1

semaglutide. That is the whole post, but I will justify it.

Everything else people worry about in c/researchpeptides is downstream of it. Titration speed, reflux, the endless dose arguments — most of it resolves if you sort semaglutide out first, and almost nobody does.

I say this having got it wrong for 4 months. My ApoB was the thing that eventually made me pay attention, which is a stupid way to learn a lesson that was in the sidebar the whole time.

11,821 up / 503 down96% upvoted49 commentsid 9uac7o29 Aug 2024

49 comments

20 in this archive, depth 4

best — the order this archive was captured in

u/camila_mensa-10 points·1 year ago

The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.

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u/leila_vasquez1.4k points·1 year ago
no
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u/leila_silva914 points·1 year ago

the injection-site soreness passes. i promise. not medical advice.

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u/units_not_mgMOD524 points·1 year ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/noor_hovland729 points·1 year ago

stalled at 1.7mg, went up, and regretted it, the stall would have broken anyway

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u/customs_seizure_sid1k points·1 year ago

my triglycerides moved before the scale did and i nearly missed it

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u/gustav_solbergOP513 points·1 year ago

The thing nobody prepared me for was that the appetite does not come back for a long time after you stop.

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u/nikhil_teixeira266 points·1 year ago

The confident tone is doing a lot of work that the evidence is not.

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u/prior_auth_painappeals682 points·1 year ago

stalled at 1.0mg, went up, and regretted it, the stall would have broken anyway

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u/gustav_solbergOP421 points·1 year ago

I did the fast version. 2.4mg to 2.5mg in 15 weeks. Spent a weekend learning why the schedule exists.

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u/niels_lindqvist179 points·1 year ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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u/camila_sandvik705 points·1 year ago

Every time this gets posted it hits the front page and every time someone has to re-explain it.

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u/rasmus_kimani210 points·1 year ago

titration speed is food noise plus side effects, period

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u/camila_sandvik101 points·1 year ago

titration speed is food noise plus side effects, period

Disagree on that part. 98.7% and 98.9% on the same vial is normal.

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u/alcohol_aversion366 points·1 year ago

Cosigning. The slow route gets the outcome, the fast route gets you the side effects.

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[removed]250 points·1 year ago

[removed by moderator]

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u/sofia_wikstrom175 points·1 year ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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u/b12_baseline112 points·1 year ago·edited

Right, and the corollary is that stopping escalation does not reset your tolerance, it just pauses the clock.

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u/endpoint_creep70 points·1 year ago

Slight fix: the number was 95.1, not 94.2. Decimal point, but a fairly consequential one.

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u/chidi_demir41 points·1 year ago

the 2.4mg dose is not the target, it is just what the pen goes up to

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Everything semaglutide: branded pens, compounded vials, oral formulations and the research-grade material people reconstitute themselves. Titration schedules, side-effect management, plateau troubleshooting and long-term maintenance. Dose questions are welcome; "what dose should I take" answers are not, because nobody here is your prescriber.

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