weekly dosing: the version I wish someone had shown me in week 1
Confession thread, sort of.
I went from 0.5mg to 12.5mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 24 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway.
So now I have sulphur burps I did not need and a data point I cannot interpret. Two lessons in one.
Posting it in the hope that somebody at week 13 reads it before doing the same thing.
best — the order this archive was captured in
Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.
okay but what dose of sema are you on
the injection-site soreness passes. i promise. not medical advice.
Did anything else change in the same window? Sleep, protein, steps, anything?
Did anything else change in the same window?
Disagree on that part. 99.0% and 98.9% on the same vial is normal.
okay but what dose of sema are you on
the fatigue passes. i promise. not medical advice.
Sweden here. Waited 9 months on an NHS list, gave up, went private, and the cost was half what I expected but the admin was worse.
The thing nobody prepared me for was that the appetite does not come back for a long time after you stop.
nope, 0.25 counts, it is just not the dose most people stay on
Yeah, 31 weeks on 2.5mg, same pattern, same timing.
week 49 on the pen, 46kg down, this is the answer
Titration speed is a side-effect dial far more than an efficacy dial.
week 48 on the pen, 41kg down, this is the answer
the quiet is real. the food noise just stops.
pens are overpriced, research vials are research grade, same molecule different price
the quiet is real.
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
Every time this gets posted it hits the front page and every time someone has to re-explain it.
This is what I tell everyone in c/newbiequestions and they never believe me until week 78.
This matches my experience almost exactly on the Ozempic pens. The titration is the whole point.
Is that purity or net peptide content? They are not the same number.
Strongly agree. If it is not working at 5mg after 80 weeks, going up is not automatically the answer.
week 2 on the pen, 8kg down, this is the answer
the quiet is real. the food noise just stops.
What was the method? "HPLC" is a technique, not a method.
nope, 0.25 counts, it is just not the dose most people stay on
The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.
Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.
pens are overpriced, research vials are research grade, same molecule different price
- 1Dead space in the needle hub holds a small but non-trivial volume. On…8 comments in this branch · started by u/plain_titration
- 2This matches my experience almost exactly on the Ozempic pens. The titration…8 comments in this branch · started by u/camila_sandvik