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c/semaglutide·posted 1 year ago by u/ravi_sandvik

7 months in and titration is still the thing I get wrong

Question Clean Column ×2 Receipts ×1 Sourced ×3

Posting this because I searched for it and got nothing useful.

Setup: 0.5mg, week 4, sulphur burps present but not ruining anything. I changed exactly one variable — Ozempic — and tracked it for 20 weeks.

Result: a difference, but a small one, and well inside what I would call noise if someone else posted it. So I am putting it here rather than presenting it as a finding. If two or three other people have done the same thing we might actually learn something.

Not medical advice, obviously. This is one person with a spreadsheet.

6,518 up / 332 down95% upvoted39 commentsid 1fp9nr23 Jun 2025

39 comments

30 in this archive, depth 4

best — the order this archive was captured in

u/viktor_nkemelu986 points·1 year ago

The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.

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u/coa_janitormod · c/coa679 points·1 year ago

Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.

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[removed]500 points·1 year ago

[removed by moderator]

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u/ravi_sandvikOP293 points·1 year ago

Kept a public log for 44 weeks. The comments are what kept it going, honestly. Accountability from strangers works.

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u/anya_antonsen1.3k points·1 year ago

Cosigning. The slow route gets the outcome, the fast route gets you the side effects.

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u/ferritin_low503 points·1 year ago

Is that purity or net peptide content? They are not the same number.

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u/prior_auth_painappeals598 points·1 year ago

That is net peptide content, not purity. Different number, different meaning.

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u/ismael_chukwu442 points·1 year ago

Strongly agree. If it is not working at 0.5mg after 38 weeks, going up is not automatically the answer.

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u/helga_vermeulen211 points·1 year ago·edited

Yeah, 87 weeks on 2.4mg, same pattern, same timing.

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u/elodie_grimaldi110 points·1 year ago·edited

Not to be pedantic but weekly dosing and 2.4mg are being used interchangeably and they are not interchangeable in real life.

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load more comments (3) →
u/anya_antonsen240 points·1 year ago
controversial sort brought me here and it was worth it
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u/rania_diallo67 points·1 year ago

okay but what dose of sema are you on

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u/ravi_sandvik67 points·1 year ago

Did anything else change in the same window? Sleep, protein, steps, anything?

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u/zeynep_zielinski41 points·1 year ago

Is that purity or net peptide content? They are not the same number.

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u/diego_sorensen0 points·1 year ago

the quiet is real. the food noise just stops.

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u/ahmed_abubakar-10 points·1 year ago

the sulphur burps passes. i promise. not medical advice.

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u/meta_analysis_mo1 point·1 year ago

my ferritin moved before the scale did and i nearly missed it

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u/kavya_radich47 points·1 year ago

the quiet is real. the food noise just stops.

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u/units_not_mgMOD239 points·1 year ago

Tracking number removed. It identifies both ends of a shipment.

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u/ravi_bergstrom147 points·1 year ago

Cosigning. The slow route gets the outcome, the fast route gets you the side effects.

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u/oskar_ibarra77 points·1 year ago

the 2.4mg dose is not the target, it is just what the pen goes up to

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u/plain_titration30 points·1 year ago

okay but what dose of sema are you on

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u/anya_erdogan283 points·1 year ago

Small correction: the trial was 17 weeks, not 9. Does not change your point but people will quote it.

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u/dead_space_doug0 points·1 year ago

How long were you at 7.5mg before you moved up?

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u/slow_logbook_notes108 points·1 year ago

okay but what dose of sema are you on

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u/katrin_diallo34 points·1 year ago

This matches my experience almost exactly on the Ozempic pens. The titration is the whole point.

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u/ravi_sandvikOP46 points·1 year ago

Did you test the vial you received or are we going off the vendor COA?

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