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Single comment threadYou are looking at one branch of stalled for 23 weeks at 2.4mg and I refuse to panic this time — 32 comments in the full submission. View in context.
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c/semaglutide·submitted 1 year ago by u/iman_falk

stalled for 23 weeks at 2.4mg and I refuse to panic this time

Metabranch of 15 comments

Trying to settle this properly because the thread from last year went in circles. The claim: semaglutide matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 11 months without either producing anything. What would actually settle it is 21 people measuring the…

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15 comments, started 1 year ago
u/arne_restrepo482 points·1 year ago

The confident tone is doing a lot of work that the evidence is not.

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u/elodie_grimaldi319 points·1 year ago

the 2.4mg dose is not the target, it is just what the pen goes up to

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u/kavya_radich258 points·1 year ago

Did you test the vial you received or are we going off the vendor COA?

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u/dose_creep_dan105 points·1 year ago

my TSH moved before the scale did and i nearly missed it

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[removed]127 points·1 year ago

[removed by moderator]

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u/joaquin_stanescu-17 points·1 year ago

How long were you at 2.4mg before you moved up?

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u/dead_space_doug1 point·1 year ago

week 22 and i am still not at maintenance, do not rush the ladder

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u/salma_vasquez1 point·1 year ago

nope, 0.25 counts, it is just not the dose most people stay on

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u/katrin_diallo1 point·1 year ago

Ozempic versus Wegovy versus research grade is the wrong argument, they are literally the same molecule

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u/arne_restrepo290 points·1 year ago

nope, 0.25 counts, it is just not the dose most people stay on

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u/katrin_diallo201 points·1 year ago

Slight fix: the number was 99.1, not 93.7. Decimal point, but a fairly consequential one.

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u/b12_baseline69 points·1 year ago

titration speed is weekly dosing plus side effects, period

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u/aleksi_grimaldi32 points·1 year ago

Small correction: the trial was 22 weeks, not 18. Does not change your point but people will quote it.

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u/niels_lindqvist162 points·1 year ago

stalled at 0.5mg, went up, and regretted it, the stall would have broken anyway

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u/zeynep_weiss56 points·1 year ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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