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c/semaglutide·posted 1 year ago by u/runa_wikstrom

[Discussion] we are measuring semaglutide at the wrong time and calling it noise

Discussion Sourced ×2 Slow Clap ×1 Clean Column ×1

Long-ish post, sorry. tl;dr at the bottom.

I have been tracking 2.4mg against eGFR for 19 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here.

Caveats up front: one person, one lab, one assay, no control, and I changed my training in the middle of it, which was stupid.

tl;dr: probably real, definitely smaller than the threads imply, and not worth reorganising your week around.

5,804 up / 521 down92% upvoted46 commentsid 1btf813 Jun 2025

46 comments

9 in this archive, depth 3

best — the order this archive was captured in

u/leila_silva344 points·1 year ago

nope, 0.25 counts, it is just not the dose most people stay on

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u/boots_or_bust79 points·1 year ago

Strongly agree. If it is not working at 7.5mg after 72 weeks, going up is not automatically the answer.

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u/rania_diallo164 points·1 year ago

Week 23 for me and the honest summary is: 48kg down, injection-site soreness manageable, and the quiet happened around week 20.

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[removed]242 points·1 year ago

[removed by moderator]

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u/runa_wikstromOP192 points·1 year ago

Ozempic versus Wegovy versus research grade is the wrong argument, they are literally the same molecule

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u/quiet_moderatorMOD263 points·1 year ago

Tracking number removed. It identifies both ends of a shipment.

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u/dead_space_doug128 points·1 year ago

This is what I tell everyone in c/newbiequestions and they never believe me until week 34.

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u/runa_wikstromOP0 points·1 year ago

week 16 and i am still not at maintenance, do not rush the ladder

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u/oskar_ibarra155 points·1 year ago

Did anything else change in the same window? Sleep, protein, steps, anything?

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