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c/semaglutide·posted 2 years ago by u/plain_titration

titration: the version I wish someone had shown me in week 1

PSA Well Actually ×6 Clean Column ×1 Receipts ×1

Long-ish post, sorry. tl;dr at the bottom.

I have been tracking 2.4mg against ApoB for 33 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here.

Caveats up front: one person, one lab, one assay, no control, and I changed my training in the middle of it, which was stupid.

tl;dr: probably real, definitely smaller than the threads imply, and not worth reorganising your week around.

4,005 up / 1,337 down75% upvoted48 commentsid 12f8k529 Apr 2024

48 comments

11 in this archive, depth 3

best — the order this archive was captured in

u/anya_antonsen441 points·2 years ago
the VendorInvestigate number or it did not happen
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u/freya_baptista514 points·2 years ago

Cosigning. The slow route gets the outcome, the fast route gets you the side effects.

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u/titration_marshalMOD324 points·2 years ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/vikram_ferreira0 points·2 years ago

stalled at 1.7mg, went up, and regretted it, the stall would have broken anyway

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u/freya_baptista165 points·2 years ago

Did you test the vial you received or are we going off the vendor COA?

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u/archived_thread_a45 points·2 years ago

the 2.4mg dose is not the target, it is just what the pen goes up to

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u/ferritin_low167 points·2 years ago

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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u/bilal_osei-15 points·2 years ago

The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.

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u/plain_titrationOP1 point·2 years ago

The thing nobody prepared me for was that the appetite does not come back for a long time after you stop.

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u/viktor_nkemelu98 points·2 years ago

nope, 0.25 counts, it is just not the dose most people stay on

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u/iman_falk148 points·2 years ago

titration speed is food noise plus side effects, period

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Everything semaglutide: branded pens, compounded vials, oral formulations and the research-grade material people reconstitute themselves. Titration schedules, side-effect management, plateau troubleshooting and long-term maintenance. Dose questions are welcome; "what dose should I take" answers are not, because nobody here is your prescriber.

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