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c/retatrutide·submitted 7 months ago by u/careful_gradient32

week 26 check-in — 42kg down, constipation manageable, one thing confusing me

Discussionbranch of 6 comments

Been lurking in c/sideeffects for about 12 months and finally have something worth posting. Short version: week 40, 10mg, and triple agonist is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 17 threads, and the answers split roughly down the middle. What I actually want to…

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6 comments, started 7 months ago
u/nikhil_lindqvist52 points·7 months ago

Research use material only, no human-use approval anywhere. Posts must describe what happened, not instruct strangers.

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u/trialwatch_theoMOD27 points·7 months ago·edited

Removed a chain here. The rule is one line long and it is not negotiable.

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u/two_mil_or_one10 points·7 months ago

Are you quoting phase 2 or is there phase 3 data now?

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u/solene_ilunga11 points·7 months ago

Strongly agree. Heart rate escalation needs the actual data, not impressions.

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u/careful_gradient32OP16 points·7 months ago

Dose escalation on retatrutide is steeper and faster than on semaglutide. Do not assume the titration patterns transfer.

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u/zeynep_mbeki5 points·7 months ago

Dose escalation on retatrutide is steeper and faster than on semaglutide.

Yes, exactly this, and it is the bit that took me 42 weeks to accept.

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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