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c/retatrutide·posted 4 months ago by u/anya_moreau

[Discussion] can we stop arguing about retatrutide until somebody posts a number

Discussion Receipts ×6 Cold Box ×1 Clean Column ×1

I have had 5 orders now and I keep a table, so here is the honest summary rather than a vibe.

Material has been consistent. Communication has not. Shipping has varied by about 30 days on nominally the same lane, which matters more in summer than in February.

The independent number came back 97.9% against a claimed 98.0%, which I read as agreement rather than a discrepancy — inter-lab variance on this assay is a point or two either way and treating one lab as ground truth is how people end up in pointless arguments with vendors.

Batch number is in the comments. Ask if you want the method.

3,661 up / 308 down92% upvoted20 commentsid vmw7ya12 Mar 2026

20 comments

9 in this archive, depth 3

best — the order this archive was captured in

u/clara_weiss412 points·4 months ago

I am going to push back on this slightly.

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u/soren_nkemelu271 points·4 months ago

The heart rate signal in TRIUMPH is real and concerning. Higher doses had higher mean HR changes.

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u/deleted_my_history113 points·4 months ago

I am going to push back on this slightly.

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u/ledger_modMOD157 points·4 months ago

This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.

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u/trialwatch_theotrial nerd47 points·4 months ago

Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3 compounds.

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u/andres_sorensen96 points·4 months ago

Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3 compounds.

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[removed]66 points·4 months ago

[removed by moderator]

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u/niels_lindqvist19 points·4 months ago

This is correct. Triple agonism is genuinely different.

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u/anya_moreauOP26 points·4 months ago

The glucagon component does different things than dual agonism. The muscle cramps are not just amplified versions.

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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c/retatrutide rules
  1. Retatrutide is not approved anywhere for human use. Posts must not read as usage instructions.
  2. Phase 2 numbers are not maintenance numbers. Cite the trial and the dose arm.
  3. Heart-rate and dose-escalation reports need actual measurements, not impressions.
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  5. Not medical advice. Describe what you did; never prescribe to a stranger.
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