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c/retatrutide·submitted 1 year ago by u/solene_ilunga

[Meta] proposal — a flair for glucagon posts

Cautionbranch of 7 comments

I have had 5 orders now and I keep a table, so here is the honest summary rather than a vibe. Material has been consistent. Communication has not. Shipping has varied by about 24 days on nominally the same lane, which matters more in summer than in February. The independent number came back 97.9% against a claimed…

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7 comments, started 1 year ago
u/quiet_moderatormod138 points·1 year ago

Strongly agree. Heart rate escalation needs the actual data, not impressions.

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u/isabela_nilsen93 points·1 year ago

Which trial arm and what was the n?

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u/two_mil_or_one23 points·1 year ago

Did you actually measure heart rate or is that a feeling?

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u/careful_gradient_notes18 points·1 year ago

the weight curves are unusually steep, which makes predicting individual response harder

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u/nadia_trevino8 points·1 year ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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u/lurker_for_years64 points·1 year ago

TRIUMPH data is phase 2, not phase 3, smaller n and shorter

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u/signe_villalobos41 points·1 year ago

Strongly agree.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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