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c/retatrutide·submitted 2 years ago by u/bastian_ekstrom

does retatrutide actually matter or is it forum lore at this point

Trial Databranch of 5 comments

Long-ish post, sorry. tl;dr at the bottom. I have been tracking retatrutide against eGFR for 21 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here. Caveats up front: one person, one lab, one…

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5 comments, started 2 years ago

u/aa_analysis_andy594 points·2 years ago

The heart rate signal in TRIUMPH is real and concerning. Higher doses had higher mean HR changes.

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[removed]439 points·2 years ago

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u/reflux_report312 points·2 years ago

the glucagon component changes the side effect profile, not just the efficacy

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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