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c/retatrutide·submitted 2 years ago by u/source_or_silence

triple agonist — 22 things I got wrong before I got it right

Discussionbranch of 7 comments

Confession thread, sort of. I went from 1.0mg to 15mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 13 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway. So now I have reflux I did…

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7 comments, started 2 years ago
u/cold_chromatogram_only150 points·2 years ago

heart rate and dose escalation need actual measurements, not impressions

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u/viktor_laurent92 points·2 years ago

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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u/renzo_yildiz50 points·2 years ago

triple agonism plus glucagon is a different physiological state than GIP/GLP-1 dual

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u/endotoxin_elliemicro60 points·2 years ago

Not to be pedantic but glucagon and triple agonist are being used interchangeably and they are not interchangeable in real life.

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u/solene_ilunga37 points·2 years ago

Respectfully this is a sample of one presented as a finding.

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u/careful_gradient3237 points·2 years ago

triple agonism is phase 2, do not generalise

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u/rui_only_ro22 points·2 years ago

Not to be pedantic but retatrutide and TRIUMPH are being used interchangeably and they are not interchangeable in real life.

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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