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c/retatrutide·submitted 1 year ago by u/nikhil_lindqvist

triple agonist is the most under-discussed thing in c/glp1uk

Questionbranch of 9 comments

Week 21 update. 7kg down from the start, reflux basically gone since about week 61. Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with reflux. The part that surprised me is how much of this is admin. Ordering,…

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9 comments, started 1 year ago
u/employer_carveout6 points·1 year ago

retatrutide is not approved anywhere for human use, posts must not read as instructions

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u/incretin_ivypharmacology2 points·1 year ago

triple agonism is glucagon, do not generalise

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u/injection_site_iris1 point·1 year ago

retatrutide is not approved anywhere for human use, posts must not read as instructions

Yes, exactly this, and it is the bit that took me 60 weeks to accept.

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[deleted]1 point·1 year ago

[deleted]

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u/endotoxin_elliemicro1 point·1 year ago

Disagree. What you are describing is consistent with retatrutide, not with what you concluded.

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u/nadia_norgaard1 point·1 year ago

Are you quoting phase 2 or is there phase 3 data now?

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u/nausea_notesside effects1 point·1 year ago

Are you quoting phase 2 or is there phase 3 data now?

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/viktor_laurent1 point·1 year ago

TRIUMPH data is phase 2, not phase 3, smaller n and shorter

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u/kavya_kravchenko1 point·1 year ago

Small correction: the trial was 9 weeks, not 38. Does not change your point but people will quote it.

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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