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c/reconstitution·submitted 5 months ago by u/hedda_ekstrom

[Results] 2 weeks, 15kg, and mg/mL was the hard part

Correctionbranch of 13 comments

Genuinely asking, not being difficult. Everyone in c/cagrilintide repeats that dead space is important. I believe it, but I have never seen anyone show why, and when I search I get 4 threads of people agreeing with each other. Is there a paper? Is there a measurement? Or is this one of those things that is true…

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13 comments, started 5 months ago
u/tomas_kimani35 points·5 months ago

Dead space ate 13 units on a low-volume draw. Tiny impact at 0.5mg, massive impact at 0.25mg.

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u/viktor_erdogan8 points·5 months ago

swirl, do not shake, or you are courting oxidation

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u/hedda_ekstrom3 points·5 months ago·edited

dosing errors come from people reconstituting two vials differently and forgetting which is which

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u/ilias_cabrera21 points·5 months ago

never post a calculation as advice without stating the concentration

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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